单位:李泽惠(昆明医学院附属第二医院泌尿外科昆明,650101);许绍斌 褚嘉祐(中国医学科学院医学生物研究所遗传室);郭萍 章宗籍(昆明医学院病理教研室);石勇刚(昆明医学院附属第一医院泌尿外科)
关键词:膀胱肿瘤;基因;P16;聚合酶链反应;基因缺失
摘要 目的:探讨膀胱癌的发生与P16基因缺失的关系。方法:采用双重PCR法对31例膀胱癌组织中P16基因进行检测。结果:31例膀胱癌组织中有7例存在P16基因缺失,缺失率为22.6%。结论:P16基因缺失与某些膀胱癌的发生存在一定的联系。
The deletions of P16 gene detected in bladder cancer by duplex PCR
LI Ze-hui
(Department of Urology,the Second Affiliated Hospital to Kunming Medical College,Kunming,650101)
XU Shao-bin ZHU Jia-you
(Division of Gecomics,Institute of Medical Biology,Chinese Academy of Medical Sciences)
GUO Ping ZHANG Zhong-ji
(Department of Pathology,Kunming Medical College)
SHI Yong-gang
(Department of Urology,the First Afilliated Hospital,Kunming Medical College)
Abstract Purpose:To investigate the deletion of P16 g ene in the bladder cancer.Methods:Th
